三維人體組織電磁仿真軟件平臺(tái) Sim4Life
概述
三維人體組織仿電磁真軟件平臺(tái)Sim4Life 是由瑞士IT'IS基金會(huì)研發(fā)的，已獲得瑞士CTI醫(yī)療科技獎(jiǎng)，Sim4Life平臺(tái)結(jié)合可計(jì)算人類模型、物理解算器和的組織模型，能直接分析人體真實(shí)世界和復(fù)雜技術(shù)設(shè)備，以及驗(yàn)證人體和解剖學(xué)環(huán)境之中的變化。Sim4Life采用高性能計(jì)算和最直觀GUI架構(gòu)，能實(shí)現(xiàn)精確的多物理模擬，和無盡的定制加快研發(fā)活動(dòng)，協(xié)助醫(yī)療及科研團(tuán)隊(duì)優(yōu)化和治療方法，且同時(shí)符合性和有效性的要求。
三維人體組織電磁仿真軟件平臺(tái)Sim4Life運(yùn)作流程可分成MRI/CT 3D影像重建、解剖及產(chǎn)品模型導(dǎo)入(CAD)、多樣化解算器、組織和物理模型、直觀的分析報(bào)告及硬體驗(yàn)證等階段，能夠在取得多張影像資料之后，快速進(jìn)行完整3D三維影像重建，再利用內(nèi)建產(chǎn)品模型，產(chǎn)生接近真實(shí)狀況的模擬資料。而且產(chǎn)品本身支持市面上常見的模型軟件，包含各種公開的人體解剖模型，能夠符合不同醫(yī)療環(huán)境的使用需求。
三維人體組織電磁仿真軟件平臺(tái)Sim4Life內(nèi)建為計(jì)算復(fù)雜問題所設(shè)計(jì)的運(yùn)算核心，包括EM、熱學(xué)、聲波和流體求解，醫(yī)療研究單位只要安裝在高效能電腦上，即可在最短時(shí)間內(nèi)獲得運(yùn)算結(jié)果。此外，三維人體組織仿真軟件平臺(tái)Sim4Life本身便有灌注模型，組織損傷模型和神經(jīng)元模型，均是現(xiàn)今手術(shù)過程中使用頻率的元件，特別是軟件本身可透過簡單易于操作的圖形化三維介面，協(xié)助操作者完成定義問題、離散，模擬和分析等步驟，能讓模擬結(jié)果都更接近真實(shí)結(jié)果。
一般來說，健康管理平臺(tái)上收集到的資料有兩大用途，首先是作為醫(yī)生治療前的評(píng)估參考，如用藥種類或是手術(shù)形式，其次則是將病歷資料轉(zhuǎn)換為更容易閱讀的可視化圖像。醫(yī)院或研究單位若能夠?qū)⑶笆鰞深愘Y料，輸入到多重物理模擬軟件Sim4Life時(shí)，則有助于新醫(yī)療技術(shù)開發(fā)，進(jìn)而為特定疾病研發(fā)出更有效的藥物或治療工具。
In silico
The digital revolution is extending the frontiers of medicine and medical technology. Computer modeling and simulation (CM&S), or in silico technologies, merge computational tools with biology to intuitively, precisely, and reproducibly perform complex analyses of life sciences applications. With this emerging paradigm, experimental manipulations that are infeasible or impossible to conduct in real-life experiments can be created while maintaining experimental control: the perfect complement to in vivo and in vitro studies.
ZMT provides in silico solutions to the medical device industry. Our comprehensive simulation platform, Sim4Life, provides a powerful 3D validated biological and anatomical modeling environment for optimizing the effectiveness and performance of medical devices, improving patient safety, and discovering potential new treatments. Built from the ground up, Sim4Life provides smooth and fully automated or customizable workflows for applications ranging from exploratory research and medical device development to regulatory documentation for clinical trials and device certification.
we trust
Our software tools are thoroughly and continually verified to ensure their reliability and performance requirements as they evolve.
The same effort is on validation for our expanding portfolio of targeted life sciences models and applications.
ZMT also provides test systems for validation procedures that support complex requirements with software tools optimized for test and measurement systems.
At ZMT, we leverage the combined strength of our expertise, experience, cost-effective solutions, and commitment to long and fruitful client relationships to enhance your competitive advantage during the regulatory submission process.
Phantoms Solvers & Tissue Models Validation Hardware
Sim4Life
Sim4Life is the first computational life sciences platform integrating computable human phantoms with the most powerful physics solvers and the most advanced tissue models for directly analyzing biological real-world phenomena and complex technical devices in a 3D validated biological and anatomical environment.
At the core of Sim4Life are the computable, high-fidelity 3D Virtual Population (ViP) human anatomical models. Carefully selected to fully represent global variations in human anatomy, the fully posable, morphable, and validated ViP models along with the IT'IS tissue properties database depict 15 different body types with 120 vital anatomical features and over 300 precisely identified tissues and organs. Cited and applied in hundreds of published studies and papers, the ViP models and the IT'IS material parameter database are continually and meticulously updated, refined, and expanded.
Sim4Life is a revolutionary simulation platform, combining computable human phantoms with the most powerful physics solvers and the most advanced tissue models, for directly analyzing biological real-world phenomena and complex technical devices in a validated biological and anatomical environment. The Sim4Life platform also offers leading performance with all the features expected from a multiphysics CAE/TCAD platform. Watch the Sim4Life demo video!
Computable Human Phantoms Physics Solvers Sim4Life natively supports the Virtual Population ViP 3.0 models that include integrated posing and morphing tools. Other publicly available animal and human anatomical models are also supported. All tissues are linked to a continually updated physical properties database.
| The powerful Sim4Life solvers are specifically developed for computationally complex problems; HPC accelerated for the latest computer clusters; and smoothly integrated in the most advanced coupling framework. The platform already includes EM, Thermal Acoustic, and Flow solvers. |
Tissue Models Framework The integrated tissue models enable the modeling and analysis of physiological processes. Perfusion models, tissue damage models, and neuronal models are already included in the first release of Sim4Life.
| The Sim4Life Framework efficiently facilitates all steps in complex multiphysics modeling, from defining the problem, discretizing, simulating, and analyzing to visualizing the results, with clarity and flexibility. |
Sim4Life Platform 三維人體組織電磁仿真軟件平臺(tái)Sim4Life組成 Computable Human Phantoms 可計(jì)算人類仿真軟件 | Physics Models 物理模型 | Tissue Models 組織模型 | Intuitive GUI and Workflow
直觀的圖形用戶界面及集成平臺(tái) | Licensed Modules 可模塊 |
ViP 3.0 Virtual Population | P-EM-FDTD Electromagnetics Full Wave Solvers | T-NEURO Neuronal Tissue Models | iSEG Medical Image Segmentation Tool Set | MRI M-MUSAIK M-TxCOIL M-BCAGE M-SYSSIM M-GRAD M-IMSAFE |
ViA 1.0 Animal Models | P-EM-QS Quasi-Static Electromagnetics Solvers | T-CEM43 Tissue Damage Models | MODELER Advanced Modeling Tool Set |
| Third-Party Models | P-THERMAL Thermodynamics Solvers | T-FLOWRATES Flow Rate Computational Engine | MESHER Robust & Effective Meshing | MODELING M-REMESH M-POSER |
| | P-FLOW Fluid Dynamics Solvers | | ANALYZER Versatile Postprocessor and Analyzing Tool Set | CALCULATORS M-DISPFIT M-PPCALC |
| | P-ACOUSTICS Acoustics Solvers | | PYTHON Control via Python Scripting | PROCESSING M-MATCH M-TALATLAS M-MBSAR M-PHARRAY |
| | P-CRD Convection Reaction Diffusion Solvers (coming soon) | | |
| | P-MECH Mechanical Solvers (coming soon) | | | IMPORT M-HUYGENS M-IMG M-VOX |
| | High Performance Computing Auto-Scheduler & Control ARES | |
Computable Human Phantoms-ViP 3.0 可計(jì)算三維人體組織仿真軟件-ViP 3.0 Physics Models 物理模型 Tissue Models 組織模型 Framework - Intuitive GUI and Workflow直觀的圖形用戶界面及集成平臺(tái) Sim4Life Modules - Licensed Modules可模塊 Configurations配置
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